Analysis of South Korea’s Rejuran: An in-depth explanation of the principles behind PN Fish Repair Essence, its injection costs, and how to maintain its effects.

“Is Rejuran really just a form of ‘intelligence tax’, and what exactly does it feel like after using it?”

Rejuran is known in South Korea’s medical beauty industry as the “collagen bomb,” and almost everyone has at least one bottle in their collection over the past two years. However, when I first tried it in Taiwan, each bottle cost 12,000 Taiwanese dollars. After the treatment, I only felt that my skin had become slightly more moist; otherwise, I didn’t notice any significant changes. Later, when I went to South Korea, a doctor told me that “the concentration and application method in Taiwan are different from those in South Korea.” So I tried their approach: after using three bottles in combination, a week later, a colleague asked me if I had changed my skincare products because my skin looked so good. This article outlines the principles, ingredients, prices of Rejuran, as well as some tips for choosing it.

What is Rejuran? An analysis of South Korea’s practices

Rejuran is a PDRN (Polydeoxyribonucleotide) preparation developed by the South Korean company PharmResearch. PDRN is a reparative ingredient extracted from the testicular DNA of salmon. Since the similarity between salmon DNA and human DNA is as high as 98%, it is not likely to cause any rejection reactions when absorbed by the human body.

Rejuran’s product line:

🔹 Rejuran Healer: The basic version, focusing on skin repair and hydration, is the most popular model.

🔹 Rejuran I: The enhanced version, with a higher concentration of PDRN, specifically designed for treating acne scars and promoting skin regeneration.

🔹 Rejuran HB: Contains hyaluronic acid for enhanced moisturizing effects, suitable for dry skin types.

🔹 Rejuran BQ: Specifically designed for wrinkles and aging, contains peptide ingredients.

🔹 Rejuran CN: Designed for sensitive skin, helps restore the skin’s barrier function

The practices of South Korean clinics are as follows: First, combination use – South Korean doctors rarely use a single product; instead, they often combine Healer with HB or Healer with Seoul I, adjusting the proportions according to your skin type. Second, synergistic combination – Rejuran is frequently used in conjunction with Asce+ Exosomes and Filler to enhance the effects. Third, precise application techniques – South Korean doctors use MTS to target key areas such as the Nasolabial Fold Correction and under-eye areas, followed by a machine to ensure even coverage across the entire face.

Each bottle of Rejuran contains 2 ml of the product, and usually 2 to 3 bottles are required for the entire face. The application process takes approximately 40 to 60 minutes.

What are the results? Which specific issues have been actually improved?

The biggest difference between Rejuran and ordinary hyaluronic acid injections is that it not only provides moisture but also has restorative and regenerative effects.

🧬 Repairing damaged skin: PDRN can promote cell regeneration and accelerate the repair of the skin barrier, making it ideal for use after surgeries or laser treatments.

💧 Deep moisturization: Promotes the synthesis of hyaluronic acid in the dermis, providing longer-lasting moisturizing effects than regular hyaluronic acid injections.

🌟 Improves skin quality: The skin becomes smoother, more radiant, with reduced Pores and a more even complexion.

🌸 Lightening acne scars: Rejuran I can help improve superficial acne scars and red marks left by acne.

🎯 Reducing fine lines: Long-term use can help improve superficial fine lines, but the effects are not immediately visible.

Effect timeline: 1–2 days after the treatment, the skin may show slight pinprick marks and redness. After one week, it becomes noticeable that the skin has become finer. Once a treatment course (3–5 sessions, spaced 2–4 weeks apart) is completed, the effects can last for 6–12 months – much longer than those of regular hyaluronic acid injections.

⚠️ To be objective: Rejuran is not a miracle cure that can make you look better after just one injection. The effect of the first injection may not be obvious (since the skin needs time to recover), but after completing a full treatment course, most people will notice a noticeable improvement in their skin quality.

If you want to see the actual experience of the treatment, you can refer to the reviews of Dr. Li Jin regarding precise freckle removal to understand the techniques used by South Korean doctors and the results after the procedure.

Who is this suitable for? Analysis of unsuitable groups

Ideal candidates:

✅ Post-treatment repair: Using Rejuran after laser treatments, Pico treatments, or microneedling sessions can double the effectiveness of these treatments.

✅ For those with rough skin who want to “reverse the signs of aging” – long-term use can help restore the skin to a younger state.

✅ For those with sensitive skin or damaged skin barriers – Rejuran CN is specifically designed to help repair these barriers.

✅ For those with acne scars and red marks left by acne — Rejuran I is quite effective in treating superficial acne scars.

✅ For those who desire longer-lasting results than regular hyaluronic acid injections – the effects of Rejuran can last for 6 to 12 months.

Not suitable for:

❌ For those allergic to fish protein: PDRN is derived from salmon DNA, so people with fish allergies should use it with caution.

❌ Women who are pregnant or breastfeeding

❌ People with active inflammation on their faces (severe acne, dermatitis)

❌ For those with limited budgets who only plan to try it once – Rejuran requires at least one treatment course to be effective; a single application won’t yield significant results.

❌ For those who expect immediate results: The effects of Rejuran are gradual and require patience.

What are the differences between South Korea and Taiwan? A comparison of technology and results.

Rejuran is a brand originating from South Korea, and its advantages in the South Korean market are quite evident.

Product freshness and price: In South Korea, the price of Rejuran is much lower than overseas. A bottle of Healer costs approximately 98,000 to 120,000 won in South Korea (equivalent to around 1,900 to 2,800 New Taiwan dollars), while in Taiwan it ranges from 8,000 to 12,000 New Taiwan dollars, representing a difference of 3 to 4 times. Moreover, products purchased from clinics in South Korea are fresher and stored under better conditions.

Concentration and combination: South Korean doctors have extensive experience in using Rejuran – they know how to combine different product lines and how to adjust the concentration and dosage according to individual skin types. Some clinics in Taiwan simply use Rejuran as a regular hyaluronic acid injection, failing to utilize its restorative potential.

Counterfeit issues: Due to the immense popularity of Rejuran, many counterfeit products have appeared on the market. In South Korea, legitimate clinics always open the packages and display the batch numbers on-site. However, the origin of products from overseas clinics may not be reliable; if you decide to receive treatment in Taiwan, make sure to confirm that the product is genuine and produced by PharmResearch in South Korea.

Combination treatments: In South Korea, clinics often combine Rejuran with Pico, lasers, and HIFU. First, destructive treatments such as Pico or laser are performed, followed by Rejuran for recovery, resulting in doubled effects. In Taiwan, however, there are relatively fewer such combination treatment options available.

What is the approximate price? A summary of the market situation in South Korea in 2026.

The prices of Rejuran in South Korea are calculated based on different product lines:

Rejuran Healer (Basic Version): ¥80,000 – ¥120,000 per bottle (approximately NT$1,900 – NT$2,800 per unit)

Rejuran I (Enhanced Version): ¥910,000 to ¥150,000 per bottle (approximately NT$2,400 to NT$3,500)

Rejuran HB (moisturizing version): ¥990,000 to ¥130,000 per bottle (approximately NT$2,100 to NT$3,100).

Rejuran BQ (wrinkle-reducing version): ¥120,000 to ¥180,000 per bottle (approximately NT$2,800 to NT$4,300).

Full-face combination package (2-3 bottles): ¥920,000 to ¥350,000 (approximately NT$4,700 to NT$8,300)

A package of 3 treatments costs between ¥9.5 million and ¥8 million (approximately NT$12,000 to NT$19,000) – which is 25% to 35% cheaper than paying for each treatment individually.

💡 Purchase advice: It’s better to start with the Healer version; there’s no need to upgrade everything at once. If you feel the effects are not sufficient after 2–3 treatments, you can then upgrade to the Seoul I version or combine it with Asce+ Exosomes. Many clinics tend to promote “full premium packages,” but in fact, the basic version is sufficient for most people.

You can also learn about the repair effects and prices of Rejuran combined with laser treatments by checking out Dr. Cui Karin’s barrier repair laser therapy.

What should I pay attention to regarding the risks associated with the treatment and the recovery period?

The risks associated with Rejuran are similar to those of hyaluronic acid injections, but there are some particular precautions to take:

Common side effects:

🔴 After the treatment, there may be tiny puncture marks and red spots, which will disappear within 24 to 48 hours.

🔴 Slight swelling, especially around the eyes and corners of the mouth

🔴 In rare cases, some individuals may experience “allergic reactions” such as redness and itching (if they are allergic to fish protein).

🔴 Your skin might become drier in the first 1-2 days after treatment (this is due to the process by which PDRN absorbs moisture).

Special Note:

⚠️ Swordfish DNA allergy – Although rare, if you are allergic to seafood or fish proteins, be sure to inform your doctor beforehand.

⚠️ Within a week after the treatment, small bumps may appear on the skin. This is a normal reaction of PDRN in the process of skin repair and usually subsides within 3 to 5 days.

⚠️ Do not administer it simultaneously with vitamin C injections, as this may affect the stability of PDRN.

Postoperative care:

✦ Do not get the area wet or apply any makeup within 24 hours after the treatment.

✦ Avoid saunas and intense physical exercise within 3 days.

✦ Do not undergo any other invasive treatments within a week.

✦ Drink plenty of water, maintain proper hydration (by using face masks), and protect your skin from the sun.

In summary: Is this treatment really worth undergoing?

Rejuran is the most worthwhile investment in terms of long-term skincare treatments within South Korea’s medical aesthetics industry. It is not a quick-fix solution that produces immediate results; rather, it functions more like a “skin health supplement.” By undergoing several treatment sessions in a consistent manner, one can experience a significant improvement in skin quality.

South Korea has obvious advantages when it comes to Rejuran treatments – genuine products from the manufacturer, the freshest supplies, the lowest prices, and doctors with the most experience. If you are already planning to undergo medical beauty procedures in South Korea, adding Rejuran to your treatment plan will definitely offer excellent value for money.

Key points when choosing a clinic: Make sure it is an authentic PharmResearch product (check the packaging on-site); ensure that the doctor has experience administering PDRN injections; and avoid being pressured into purchasing overly expensive packages – the basic package is usually sufficient.

For more information on booking medical beauty treatments in South Korea, please visit “About Us”.

How to make an appointment

In South Korea, there are only two legitimate channels for booking medical beauty treatments; any other channels carry the risk of encountering scams.

Route A: Direct connection via WeChat → Add s-sourire → One-on-one pre-operative assessment, immediate inquiry about the director’s schedule, access to internal discounts, and Chinese-speaking translation services available.

Route B: BeautsGO – Let’s Enhance Each Other (mini-program) → Search for “BeautsGO” on WeChat → Enter the hospital’s English name to book directly → Transparent price comparisons, exclusive platform discounts, and a dedicated green channel for certified services. If you want to talk to someone with experience, please add me on WeChat: s-sourire. If you want to talk to someone with experience, please add me on WeChat: s-sourire. If you want to talk to someone with experience, please add me on WeChat: s-sourire.