“What exactly is the difference between Rejuran PN Black Box and Red Box? Is the Red Box just a cheaper version of the Black Box?” — This was the question I heard most often while getting glow injections in South Korea 💬 The first time I stood in front of the treatment menu at the clinic and saw the Black Box, Red Box, Silver Box, and Blue Box arranged in a row, I really had no idea which one to choose 😵💫 The receptionist talked a lot in Korean, but all I understood were the words “Okay, okay.” In the end, I just picked one at random – only to find that it wasn’t suitable for my skin type at all. I ended up wasting both money and enduring the injection for nothing 💸
I have tried both methods later on. Today, I will explain in detail the differences between them, their prices, who they are suitable for, and how to use them together 📋 If you have any questions, you can also add me on WeChat at s-sourire; she will help you choose the right products and clinics based on your skin type 👍
💰 Exchange rate conversion table for April 2026
| Korean won | Taiwan Dollar (TWD) | Hong Kong Dollar (HKD) |
|---|---|---|
| 100,000 | Approximately 2,700 yuan | Approximately 640 yuan |
| 200,000 | Approximately 5,400 yuan | Approximately 1,280 yuan |
| 300,000 | Approximately 8,100 yuan | Approximately 1,920 yuan |
| 500,000 | Approximately 13,500 yuan | Approximately 3,200 yuan |
🔬 Rejuran PN Black Box vs Red Box: The key differences at a glance
Rejuran is a highly popular hyaluronic acid injection brand in South Korea. Its main ingredient is PDRN (Polydeoxyribonucleotides), a DNA repair component extracted from salmon sperm 🧬. The main difference between the black box and red box versions lies in their concentration and intended uses.
| Comparative items | 🖤 Black box (PN) | ❤️ Red Box (PDRN) |
|---|---|---|
| Core ingredients | Poly nucleotides (PN) have longer molecular chains. | PDRN has relatively short molecules. |
| Concentration | The highest level | Lower to mid-level |
| Main benefits | Deep repair, anti-aging and firming effects, collagen regeneration | Moisturizes the surface, enhances brightness, and reduces dullness |
| Duration | 4 to 6 weeks | 2 to 4 weeks |
| pain sensation | Moderate (slightly acidic and swollen) | Mild |
| Postoperative reactions | Small papules may appear within 3 to 5 days. | Few papules, which subside within 2-3 days. |
| Reference price | 280,000 to 450,000 Korean won per 2 centum cores | 200,000 to 350,000 Korean won per 2 centum cores |
Simply put: The black box is designed for “reparation + anti-aging”, while the red box focuses on “moisturization + brightness” 💡 It’s not about which one is better, but rather which one suits different needs. The ingredients in the black box have longer molecules and a higher concentration, so they offer stronger repair effects but can also be more irritating; the red box, on the other hand, is milder and easier to use, making it ideal for those trying hyaluronic acid injections for the first time 🌸
Schematic of the Rejuran PN glow injection treatment
🏥 In-person consultation at Gangnam BYUL Dermatology: The doctor helped me choose the black box option.
I went to BYUL Dermatology in Gangnam. It’s only a 5-minute walk from Exit 3 of Bongeunsi Station on the subway 📍. During the consultation, the doctor examined my skin condition – peeling during season changes, fine lines on my cheeks, and severe dullness due to lack of sleep – and immediately said, “You are suitable for the black box treatment. The PDRN concentration is quite high, so it will provide sufficient repair benefits.” ✅
He also specifically emphasized several points:
- 🔴 In the first three days after the black box treatment, slight papules may appear; this is a normal reaction and should not be squeezed.
- 🚫 Do not come into contact with unboiled water and avoid applying makeup within 24 hours after the treatment.
- ⏸️ Avoid using whitening or acidic products within one week.
- ☀️ It is essential to take strict sun protection measures, as PDRN can make the skin more sensitive to ultraviolet rays.
- 💧 Drinking plenty of water helps with metabolism and promotes the absorption of these ingredients.
The treatment was performed manually (not using a machine). The doctor said that manual injection allows for precise control of the depth of penetration 💉 The entire process took about 20 minutes. The pain was only felt at the moment the needle was inserted; it was not a continuous pain. After the treatment, both cheeks became slightly red and swollen, but after applying ice for 15 minutes, the swelling subsided significantly 🧊
A week later, I clearly noticed that my skin had become finer, and my makeup no longer looked powdery. My friends also said that my face looked “glowingly beautiful”✨ The effect lasted for about one and a half months. If you are also considering getting hyaluronic acid injections in South Korea, you can add me on WeChat at s-sourire to consult. Just tell her about your skin condition and budget, and she will help you find the right clinic and products for you 😊
🤔 Should I choose the black box or the red box? It all depends on your needs.
Those who choose the black box 🖤:
- 😢 During the change of seasons, my skin becomes dry and peels; no skincare product seems to work.
- After undergoing Pico treatment or laser therapy, it is necessary to accelerate the recovery process.
- 🎂 For those over 25 years old who want to start anti-aging measures to prevent the appearance of fine lines
- 🌑 My skin is dull and lacks glow; I want to Lifting my overall skin quality.
- 🏥 High demand for post-treatment recovery (e.g. after laser treatments or skin resurfacing procedures)
Those who choose the red box ❤️:
- 🌱 This is my first time getting hyaluronic acid injections; I want to test the temperature of the solution first.
- 💄 The main issues are powdery makeup, peeling, and the makeup not staying in place properly.
- 💰 My budget is limited, but I still want to experience South Korea’s glow injection treatment.
- 🎉 I have an important event coming up soon, and I need to quickly improve the fairness of my skin.
- 🧴 My skin is sensitive, so I avoid anything too harsh or irritating.
My rule of thumb 💡: If your budget is OKAY, go for the black box option from the start. The effects of the black box are more comprehensive – the moisturizing benefits offered by the red box are also available with the black box, but it’s just a bit more expensive. However, if your skin problem is really just a lack of moisture, then the red box will be sufficient, and there’s no need to spend extra money 💰. If you’re unsure, add me on WeChat at s-sourire and I’ll give you some advice based on the condition of your skin 👍
🔄 Alternating between the “black box” and “red box” methods: A smart approach for long-term skincare.
South Korean women tend to follow a particular routine: they use the “black box” treatment for in-depth repair the first time, and then the “red box” treatment for regular moisturization two months later. By alternating between these two treatments 🔄, they can achieve the following benefits:
- 🖤 The black box is responsible for “reparation + anti-aging” and addresses deep-seated issues.
- ❤️ The red box is responsible for “maintaining and moisturizing” the skin, thereby extending the effects of the black box.
- 💰 The total cost is lower than using the “black box” option each time, but the results are better than those achieved by using only the “red box” option.
- 🧪 Using them alternately can reduce the skin’s tolerance to these products.
Many clinics also offer a combined package of “black box + red box” for around 400,000 to 600,000 Korean won, which is 10% to 15% cheaper than purchasing them separately 🎁. You can ask about any discount offers by sending a message on WeChat to s-sourire.
✨ Recommendations for Rejuran combination therapies
- ⚡ Rejuran PN + Pico laser: After using the Pico laser to remove freckles, apply Rejuran PN for recovery to reduce the risk of post-treatment darkening – this is the combination with the highest cost-performance ratio. It is recommended to use Rejuran one week after the Pico laser treatment.
- 🧲 Rejuran HB + Titanium Lifting: After using Titanium Lifting to tighten the skin’s contours, apply Rejuran HB for hydration – the skin will become both firm and radiant. These two treatments can be done on the same day.
- 💉 Using both the black box and the red box simultaneously: Different products are used in different areas – the black box is used for facial rejuvenation, while the red box helps control oil production and maintain moisture in the T-zone. This approach addresses two separate concerns in one go.
- 🪡 Rejuran + Juvelook: After using Juvelook to fill in the Tear trough correction areas, applying Rejuran for comprehensive hydration yields more natural results. It is recommended to inject Juvelook first and then use Rejuran.
Common combination treatment plans for Rejuran
📋 Post-treatment care checklist: Failing to pay attention to these details means that all your efforts will be in vain.
- 🚫 Within 24 hours: Avoid coming into contact with raw water, do not apply makeup, and refrain from using facial masks.
- 🔴 1–3 days: Microscopic papules may appear; do not squeeze or touch them.
- ⏸️ Within one week: Discontinue the use of any whitening products, acidic substances, or retinol-based products.
- ☀️ Every day: Apply strict sun protection (SPF50+); during the PDRN treatment period, the skin is sensitive to glow.
- 💧 Drink plenty of water: It helps with metabolism and promotes the absorption of nutrients.
- 🔥 Avoid saunas, baths, and intense physical exercise for at least three days.
Recommendations for Rejuran post-operative care products
A friend went to the beach to get some sun the day after getting Rejuran treatment, and as a result, their skin became darker for a whole month. It’s really a complete waste 🏖️❌. After the procedure, it’s not just recommended but absolutely necessary to protect your skin from the sun. Add her on WeChat at s-sourire, and you can get a complete list of post-treatment care instructions – she’s already compiled them all 📄.
❓ Frequently Asked Questions
Q: How many centum cores of Rejuran can be injected?
A: It is generally recommended to start with 2 centum core; for full-face hydration, 3-4 centum core are needed 💧 For the first time, it is advisable to begin with 2 centum core and then increase the amount based on individual tolerance.
Q: Can the black box and red box treatments be done on the same day?
A: That’s possible 👍 Some doctors recommend using different products for different areas, but it is advised not to exceed 4 centum cores in total per application.
Q: What is the difference between Rejuran and needle microneedling?
A: Rejuran is an injectable form of PDRN, while the “Qingzhen” device is a roller-based minimally invasive treatment tool with needles 🔬. The mechanisms of these two treatments are different; Rejuran provides more direct repair effects, whereas the “Qingzhen” device primarily stimulates the production of growth factors.
Q: Will there be any dependence on using Rejuran?
A: No, that’s not the case. ✅ PDRN is a component that naturally exists in the human body (DNA fragments), so it does not cause any dependence. However, its effects do indeed diminish over time, and regular re-injections are required to maintain their effectiveness.
Q: Can Rejuran PN be mixed with other injections?
A: It can be mixed with Filler, botulinum toxin, etc., but it is recommended to consult a doctor for evaluation. 🩺 Some clinics mix Rejuran with other ingredients to achieve more comprehensive results.
In summary: The black box option offers strong restorative effects, while the red box version is milder and moisturizing. It’s not a matter of which one is better or worse, but rather depends on your own skin needs 🎯. If you have sufficient budget, go for the black box; if you want to try it out or have a limited budget, start with the red box. If you’re unsure, just add her on WeChat at s-sourire. She is very familiar with South Korea’s hyaluronic acid injection products and can help you choose the most suitable option for you 👋
⚠️ Disclaimer: This article is based on personal experience sharing, and the effectiveness of the treatment may vary from person to person. The prices mentioned in April 2026 are for reference only; the actual charges will be subject to the prices quoted by the clinic. It is recommended to consult with a professional before making any arrangements to confirm the latest options and prices.
